Thermo Fisher Scientific RPL29 Polyclonal Antibody, MaxPab
RPL29 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF에 적합합니다. 인간 시료 반응성이 있으며 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 버퍼에 보존제를 포함하지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RPL29 (NP_000983.1, 1 a.a. approximately 157 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMSARAE AIKALVKPKE VKPKIPKGVS RKLDRLAYIA HPKLGKRARA RIAKGLRLCR PKAKAKAKDQ TKAQAAAPAS VPAQAPKRTQ APTKASE
Target Information
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.
Different members of this family show distinct substrate specificities for MAPKs, tissue distribution, subcellular localization, and expression inducibility by extracellular stimuli.
This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. It is evenly distributed in both the cytoplasm and the nucleus and is widely expressed in various tissues and organs, with expression elevated by stress stimuli. Three transcript variants encoding two different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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