Thermo Fisher Scientific MRPL12 Monoclonal Antibody (S1)
Human MRPL12 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot과 ELISA에 적합함. Unconjugated 형태로 제공되며, -20°C에서 보관. 미토콘드리아 단백질 합성 연구 및 MRPL12 기능 분석에 활용 가능.
- 카탈로그번호
- H00006182-M01A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S1 |
| Immunogen | MRPL12 (AAH02344, 1–198 a.a) full-length recombinant protein with GST tag (GST MW = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG APLDNAPKEY PPKIQQLVQD IASLTLLEIS DLNELLKKTL KIQDVGLVPM GGVMSGAVPA AAAQEAVEED IPIAKERTHF TVRLTEAKPV DKVKLIKEIK NYIQGINLVQ AKKLVESLPQ EIKANVAKAE AEKIKAALEA VGGTVVLETarget Information
MRPL12 (mitochondrial ribosomal protein L12), also known as 5c5-2, L12mt, MRPL7, or RPML12, is a mammalian mitochondrial ribosomal protein involved in protein synthesis within the mitochondrion.
MRPL12 expression increases in growth-stimulated cells due to transcriptional activation, suggesting a role as a translational regulator of mitochondrial mRNAs.
Deficiency of MRPL12 reduces cell growth rate, decreases mitochondrial ATP production, and abolishes oxidative phosphorylation.
It is cleaved during translocation across the mitochondrial membrane and forms dimers that bind the large ribosomal subunit.
MRPL12 consists of 198 amino acids, belongs to the ribosomal protein L12P family, and is highly expressed in the colon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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