Thermo Fisher Scientific WNT4 Polyclonal Antibody
Human WNT4 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal antibody로, WB 및 ICC/IF에 적합합니다. 내부 서열(aa 23-37)을 면역원으로 사용하였으며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Internal sequence corresponding to amino acids C-SNWLYLAKLSSVGS (aa 23–37) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2257215 |
Product Specific Information
- Predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
The WNT gene family consists of structurally related genes encoding secreted signaling proteins involved in oncogenesis and developmental processes such as cell fate regulation and embryonic patterning.
WNT4 is a key signaling molecule influencing the sex-determination cascade and shows 98% amino acid identity to mouse and rat Wnt4 proteins.
It plays a role in female development and prevention of testes formation, and may be associated with abnormal breast tissue proliferation.
Mutations in WNT4 can cause Rokitansky-Kuster-Hauser syndrome and SERKAL syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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