Thermo Fisher Scientific Lass4 Polyclonal Antibody
Lass4 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 사용 가능. 인간 시료 반응성 검증됨. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용.
- 카탈로그번호
- PA112928
- 판매단위
- pk
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human Lass4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2132973 |
Product Specific Information
A suggested positive control for this product is lung or embryo lysate.
Target Information
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family (LASS1–LASS6) are involved in sphingolipid synthesis.
LASS4 is a 394 amino acid endoplasmic reticulum multi-pass membrane protein that increases levels of long ceramides such as C22:0 and C24:0.
In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can elevate ceramide levels and partially correct growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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