Thermo Fisher Scientific CBF-beta (isoform 2) Polyclonal Antibody
CBF-beta (isoform 2)에 특이적인 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 고순도 제품. 인간 시료 반응성, 비결합형 액상 형태로 연구용에 최적화.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 166 and 182 of human Core-Binding Factor, Beta Subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family. It regulates genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit that enhances DNA binding by the alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, and GM-CSF promoters.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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