Thermo Fisher Scientific FBXL17 Polyclonal Antibody
Human FBXL17 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications
Tested Applications and Dilutions
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FBXL17. Recombinant protein control fragment (Product # RP-97599) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641531 |
Product Specific Information
Immunogen sequence:
CLKLQRIYMQ ENKLVTDQSV KAFAEHCPEL QYVGFMGCSV TSKGVIHLTK LRNLSSLDLR HITELDNETV ME
- Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 97%
Target Information
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif.
SCF complexes, formed by SKP1 (MIM 601434), cullin (CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F-box, and with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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