Thermo Fisher Scientific KV1.6 (KCNA6) Polyclonal Antibody
Rabbit polyclonal antibody targeting human KV1.6 (KCNA6) for IHC (paraffin) applications. Recognizes recombinant KCNA6 protein with 0.4 mg/mL concentration. Provides reliable detection of voltage-gated potassium channel proteins. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KCNA6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642911 |
Product Specific Information
Immunogen sequence:
GRGGNNGGVS RVSPVSRGSQ EEEEDEDDSY TFHHGITPGE MGTG
Antigen identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 56%
- Rat: 56%
Target Information
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes — shaker, shaw, shab, and shal — have been identified in Drosophila, and each has a human homolog.
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It contains six membrane-spanning domains with a shaker-type repeat in the fourth segment and belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with KCNA1 and KCNA5 on chromosome 12.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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