Thermo Fisher Scientific CDH18 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CDH18. Recombinant protein control fragment (Product #RP-90592). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDH18,uniProtId:Q13634-1,ncbiNodeId:9606,antigenRange:263-411,antigenLength:790,antigenImageFileName:PA5-53162_CDH18_Q13634-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53162_CDH18_Q13634-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639588

Product Specific Information

Immunogen sequence: DNPPRFPQKH YQLYVPESAQ VGSAVGKIKA NDADTGSNAD MTYSIINGDG MGIFSISTDK ETREGILSLK KPLNYEKKKS YTLNIEGANT HLDFRFSHLG PFKDATMLKI IVGDVDEPPL FSMPSYLMEV YENAKIGTVV GTVLAQDPD

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.

Target Information

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.