Thermo Fisher Scientific TNFRSF21 Monoclonal Antibody (6D1)
인간 TNFRSF21(Death Receptor 6)을 인식하는 Mouse IgG1 단일클론 항체로 ELISA에 적합. 비결합형 액상 형태이며 PBS buffer에 보존. 친화 크로마토그래피로 정제되어 고순도 확보. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TNFRSF21 Monoclonal Antibody (6D1)
Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D1 |
| Immunogen | TNFRSF21 (AAH17730.1, 373–655 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SSRTLKKGPR QDPSAIVEKA GLKKSMTPTQ NREKWIYYCN GHGIDILKLV AAQVGSQWKD IYQFLCNASE REVAAFSNGY TADHERAYAA LQHWTIRGPE ASLAQLISAL RQHRRNDVVE KIRGLMEDTT QLETDKLALP MSPSPLSPSP IPSPNAKLEN SALLTVEPSP QDKNKGFFVD ESEPLLRCDS TSSGSSALSR NGSFITKEKK DTVLRQVRLD PCDLQPIFDD MLHFLNPEEL RVIEEIPQAE DKLDRLFEII GVKSQEASQT LLDSVYSHLP DLL
Target Information
DR6 (Death Receptor 6) is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. DR6, a newly cloned death domain-containing receptor in the TNFR family, interacts with the adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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