Thermo Fisher Scientific TNFRSF21 Monoclonal Antibody (6D1)

Thermo Fisher Scientific TNFRSF21 Monoclonal Antibody (6D1)

Applications

• ELISA (ELISA)
  Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
SSRTLKKGPR QDPSAIVEKA GLKKSMTPTQ NREKWIYYCN GHGIDILKLV AAQVGSQWKD IYQFLCNASE REVAAFSNGY TADHERAYAA LQHWTIRGPE ASLAQLISAL RQHRRNDVVE KIRGLMEDTT QLETDKLALP MSPSPLSPSP IPSPNAKLEN SALLTVEPSP QDKNKGFFVD ESEPLLRCDS TSSGSSALSR NGSFITKEKK DTVLRQVRLD PCDLQPIFDD MLHFLNPEEL RVIEEIPQAE DKLDRLFEII GVKSQEASQT LLDSVYSHLP DLL

Target Information

DR6 (Death Receptor 6) is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. DR6, a newly cloned death domain-containing receptor in the TNFR family, interacts with the adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.

Usage Notice

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.