Thermo Fisher Scientific BCAS4 Polyclonal Antibody
BCAS4 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간 및 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [참고 문헌 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [참고 문헌 없음]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCAS4 (Accession Q8TDM0), corresponding to amino acid residues Q38–D88 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850906 |
Product Specific Information
Antibody detects endogenous levels of total BCAS4.
Target Information
The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by cloning a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is found only in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines.
The role of BCAS4 is unknown, but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting that BCAS4 may play roles in multiple tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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