Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI2D2), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Voltage-gated potassium (Kv) channels are key components of potassium currents in the heart and central nervous system.

• In the heart, Kv4 channels participate in the repolarization phase of the action potential.
• In the brain, these channels prevent reverse-propagation of action potentials.

KChIPs (Kv channel interacting proteins) are calcium-binding proteins associated with Kv4 channels, modulating their function.
There are three known KChIPs:

1. KChIP1 – expressed in the brain
2. KChIP2 – expressed in brain, heart, and lung; three isoforms (a, b, c)
3. KChIP3 – also known as calsenilin or DREAM, expressed in brain and testis

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.