Thermo Fisher Scientific TACR1 Polyclonal Antibody
TACR1 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal antibody로, 인간 및 마우스에 반응합니다. WB 및 ICC/IF에 적합하며, 고순도(Ammonium sulfate precipitation)로 정제된 액상 시약입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA518712
- 판매단위
- pk
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Thermo Fisher Scientific TACR1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EIPGDSSDRYHEQ) corresponding to internal amino acids of TACR1 (aa 227–240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984223 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology
- Tested in Peptide ELISA (antibody detection limit dilution: 1:128,000)
Target Information
Tachykinin Receptor 1 (TACR1), a member of the Tachykinin Receptor subfamily, mediates phosphatidylinositol metabolism via the tachykinin substance P (neurokinin 1).
It plays roles in depression, anxiety, stress management, behavioral regulation, neuronal survival, and cardiovascular and respiratory functions.
TACR1 is implicated in rheumatoid arthritis and osteoarthritis progression.
Two variants are produced by alternative splicing.
Primarily expressed in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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