Thermo Fisher Scientific XRCC5 (Ku86/Ku80) (Thyroid-Lupus Autoantigen) Recombinant Rabbit Monoclonal Antibody (XRCC5/8093R)
XRCC5(Ku86/Ku80) 단백질을 인식하는 재조합 토끼 단클론 항체로, 사람 시료에 반응합니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 고순도의 Protein A/G 정제 항체입니다. DNA 이중가닥 절단 복구 연구에 유용합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | XRCC5/8093R |
| Immunogen | Recombinant fragment (around aa300–500) of human XRCC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and completion of V(D)J recombination. This gene complements the Chinese hamster xrs-6 mutant defective in DNA double-strand break repair and V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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