Thermo Fisher Scientific PYDC1 Monoclonal Antibody (OTI1A4), TrueMAB
Human PYDC1 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화된 TrueMAB 형식. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. NF-kappa-B 신호 조절 연구에 적합. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A4 |
| Immunogen | Full length human recombinant protein of human PYDC1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation.
It suppresses kinase activity of the NF-kappa-B inhibitor kinase (IKK) complex, reduces expression of NF-kappa-B inducible genes, and inhibits NF-kappa-B activation by cytokines and LPS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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