Thermo Fisher Scientific Fibrinogen gamma Monoclonal Antibody (5A6)
FGG 단백질을 검출하는 Thermo Fisher Scientific의 단클론 항체로, WB, ICC/IF, ELISA에 적합합니다. 인간 및 마우스 시료에 반응하며 비결합형 액상 형태로 제공됩니다. 연구용으로 혈액 응고 관련 단백질 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A6 |
| Immunogen | Purified recombinant fragment of human FGG expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet Ice |
| RRID | AB_11157851 |
Product Specific Information
MA5-15902 targets FGG in indirect ELISA, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human FGG expressed in E. coli.
MA5-15902 detects FGG, which has a predicted molecular weight of approximately 52 kDa.
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains.
Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots.
Cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types.
Mutations in this gene are associated with disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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