Thermo Fisher Scientific RFTN1 Polyclonal Antibody
Human RFTN1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액에 40% 글리세롤 포함. 연구용으로 세포막 단백질 Raftlin 관련 면역반응 연구에 적합.
- 카탈로그번호
- PA583923
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific RFTN1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RFTN1. Recombinant protein control fragment (Product #RP-100953). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791075 |
Product Specific Information
Immunogen sequence:
ALHPFVQPTH EREKTPLEHI FRAILIKKTD RSQKTDLHNE GYILELDCCS SLDHPTDQKL IPEFIKKIQE AASQGLKFVG VIPQYHSSV
Target Information
Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), is a 578 amino acid cell membrane protein and lipid anchor essential for raft cell assembly and maintenance.
It modulates B-cell antigen receptor-mediated signaling and TCR signals, and plays a role in T cell-mediated immune responses.
The gene encoding Raftlin is located on human chromosome 3, which contains over 1,100 genes including chemokine receptor clusters and cancer-related loci.
Chromosome 3 also includes tumor suppressor genes such as RASSF1, HYAL1, and SEMA3B.
Genetic diseases associated with chromosome 3 include Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta, and Charcot-Marie-Tooth Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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