Thermo Fisher Scientific MYOZ2 Polyclonal Antibody
MYOZ2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합하며, 인간·마우스·랫트 반응성. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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- PA5100630
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- pk
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Thermo Fisher Scientific MYOZ2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYOZ2 (Accession Q9NPC6), corresponding to amino acid residues E71–D121 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850137 |
Product Specific Information
Antibody detects endogenous levels of total Myozenin2.
Target Information
The calcineurin-binding protein Myozenin 2, also known as calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase involved in controlling slow fiber gene expression in skeletal muscle and cardiac muscle hypertrophy.
Calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere.
During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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