Thermo Fisher Scientific RNF14 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

30 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RNF14 (NP_899645.1, 1 a.a. approximately 348 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RNF14,uniProtId:Q9UBS8-1,ncbiNodeId:9606,antigenRange:1-474,antigenLength:474,antigenImageFileName:H00009604-D01P_RNF14_Q9UBS8-1_Rabbit.svg,antigenImageFileNamePDP:H00009604-D01P_RNF14_Q9UBS8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MQFLKEETLA YLNIVSPFEL KIGSQKKVQR RTAQASPNTE LDFGGAAGSD VDQEEIVDER AVQDVESLSN LIQEILDFDQ AQQIKCFNSK LFLCSICFCE KLGSECMYFL ECRHVYCKAC LKDYFEIQIR DGQVQCLNCP EPKCPSVATP GQVKELVEAE LFARYDRLLL QSSLDLMADV VYCPRPCCQL PVMQEPGCTM GICSSCNFAF CTLCRLTYHG VSPCKVTAEK LMDLRNEYLQ ADEANKRLLD QRYGKRVIQK ALEEMESKEW LEKNSKSCPC CGTPIEKLDG CNKMTCTGCM QYFCWICMGS LSRANPYKHF NDPGSPCFNR LFYAVDVDDD IWEDEVED

Target Information

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.