Thermo Fisher Scientific GABRB2 Polyclonal Antibody
GABRB2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 및 마우스 시료에서 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS와 50% 글리세롤에 보관되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human GABRB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720104 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
GAD-65 and GAD-67 (glutamate decarboxylases) catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system, GABA functions as the main inhibitory neurotransmitter by increasing chloride conductance, which inhibits neuronal firing.
GABA activates ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as a third class called GABAC.
- GABAA and GABAC: Ligand-gated ion channels, structurally and functionally distinct.
- GABAA receptor family: Includes Rα1–6, Rβ1–3, Rγ1–3, Rδ, Rε, Rρ1, and Rρ2.
- GABAB family: Composed of GABAB R1α and GABAB R1β.
- GABA transporters: GABA T-1, T-2, and T-3 (also known as GAT-1, GAT-2, and GAT-3), which function to terminate GABA action.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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