
Thermo Fisher Scientific Caspase 7 Recombinant Rabbit Monoclonal Antibody (23GB2310)
Caspase 7 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. HEK293F 발현 시스템 기반, 비결합형 액상 포맷. 세포 사멸 연구 및 Caspase 관련 신호전달 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB2310 |
| Immunogen | A synthesized peptide derived from human pro Caspase 7 (1–42 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Caspase 7 is a member of the cysteine protease family, divided into apoptotic and inflammatory subfamilies. Unlike inflammatory caspases, apoptotic caspases are involved in cell death processes. Caspase 7 functions as an executioner caspase, activated by initiator caspases to cleave cellular substrates leading to apoptosis. It shares homology with caspases 1 and 3 and the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA produces three distinct isoforms, and its activity can be inhibited by XIAP expression. Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품 관련 이미지: MA5-52498_Caspase_7_P55210-1_Rabbit.svg, MA5-52498_Caspase_7_P55210-1_Rabbit_PDP.jpeg)
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