Thermo Fisher Scientific TLR9 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-1.0 µg/mL

View 1 publication 1 publication

Immunohistochemistry (IHC)

2 µg/mL

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Immunocytochemistry (ICC/IF)

10 µg/mL

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Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A peptide corresponding to 16 amino acids near the carboxy terminus of human TLR9. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TLR9,uniProtId:Q9NR96-1,ncbiNodeId:9606,antigenRange:1032,antigenLength:1032,antigenImageFileName:PA5-20202_TLR9_Q9NR96-1_Rabbit.svg,antigenImageFileNamePDP:PA5-20202_TLR9_Q9NR96-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11157204

Product Specific Information

A suggested positive control is mouse spleen tissue lysate.

PA5-20202 can be used with blocking peptide PEP-0330.

Target Information

The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.