Thermo Fisher Scientific NMI Polyclonal Antibody
인간 NMI 단백질을 타깃으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 응용(WB, IHC, IP)에 적합하며 항원 친화 크로마토그래피로 정제됨. 1mg/mL 농도, 4°C 보관, 연구용으로만 사용.
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Thermo Fisher Scientific NMI Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1 and 50 of human N-myc and STAT interactor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif.
The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma.
NMI mRNA shows low expression in most human fetal and adult tissues except brain, and high expression in cancer cell lines such as myeloid leukemias.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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