Thermo Fisher Scientific ZBTB7/FBI-1 Polyclonal Antibody
ZBTB7/FBI-1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, IP 등에 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 보관, 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 525 and the C-terminus (residue 584) of Human ZBTB7 (Factor Binding IST protein 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections
Target Information
ZBTB7/FBI-1 plays a key role in directing early lymphoid progenitors toward B-cell lineage by repressing T-cell instructive Notch signals. It represses transcription of the CDKN2A gene and abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5-[GA][CA]GACCCCCCCCC-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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