Thermo Fisher Scientific GSR Polyclonal Antibody
Thermo Fisher Scientific의 GSR Polyclonal Antibody는 인간 및 랫트 시료에서 GSR 단백질 검출용으로 개발된 토끼 폴리클로날 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 고순도의 액상 형태로 제공됩니다. 세포 내 항산화 방어 연구에 적합합니다.
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- PA5115332
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GSR (Accession P00390), corresponding to amino acid residues K392–T442 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899968 |
Product Specific Information
Antibody detects endogenous levels of total GSR.
Target Information
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The enzyme is a homodimeric flavoprotein and plays a central role in cellular antioxidant defense by reducing oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, an important cellular antioxidant. Rare mutations in this gene cause hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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