Thermo Fisher Scientific LRRC8A Polyclonal Antibody
LRRC8A 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ELISA에 사용 가능. 사람, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1.0–2.0 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC-P) | 2.5 µg/mL | - |
| ELISA | Assay-dependent | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | LRRC8A antibody for a 15 amino acid peptide near the amino terminus of human LRRC8A. The immunogen is within amino acids 60–110 of LRRC8A. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718724 |
Target Information
Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8A constitutes a pore-forming subunit or whether it is closely associated with the pore and mediates channel properties such as ion selectivity. Involved in B-cell development: required for the pro-B cell to pre-B cell transition. Also required for T-cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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