Thermo Fisher Scientific INCA1 Polyclonal Antibody
INCA1 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. 인간 시료에 반응하며 IHC(P) 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- PA560689
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific INCA1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human INCA1. Recombinant protein control fragment (Product #RP-93541) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642718 |
Product Specific Information
Immunogen sequence:
KKRRPCLEGM QQQGLGGVPA RVRAVTYHLE DLRRRQSIIN ELKKAQWGSS GAASEPVVLG EEGCGFPSTN EYPD
Highest antigen sequence identity to the following orthologs:
- Mouse: 64%
- Rat: 68%
Target Information
INCA1 binds to CDK2-bound cyclins and inhibits CDK2 kinase activity; binding to cyclins is essential for its CDK inhibitory function (PubMed:21540187). It inhibits cell growth and proliferation, contributing to cell cycle control. INCA1 is required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis, and inhibition of cell growth. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품 관련 항원 구조 이미지 및 PDP 이미지 존재: PA5-60689_INCA1_Q0VD86-1_Rabbit.svg, PA5-60689_INCA1_Q0VD86-1_Rabbit_PDP.jpeg)
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