Thermo Fisher Scientific MSL2 Monoclonal Antibody (OTI3B11), TrueMAB
MSL2 단백질을 표적으로 하는 Mouse Monoclonal Antibody로, Western Blot에 적합. Human 시료에 반응하며, Affinity chromatography로 정제됨. PBS/1% BSA/50% glycerol buffer에 보관되며, -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B11 |
| Immunogen | Full length human recombinant protein of human MSL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16, which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at Lys-35 (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at Lys-4 (H3K4me) and Lys-79 (H3K79me), leading to gene activation, including that of HOXA9 and MEIS1. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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