Thermo Fisher Scientific CHIA Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CHIA. Recombinant protein control fragment (Product #RP-94208). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHIA,uniProtId:Q9BZP6-1,ncbiNodeId:9606,antigenRange:234-305,antigenLength:476,antigenImageFileName:PA5-63681_CHIA_Q9BZP6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63681_CHIA_Q9BZP6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639766

Product Specific Information

Immunogen sequence: DTGSNAYLNV DYVMNYWKDN GAPAEKLIVG FPTYGHNFIL SNPSNTGIGA PTSGAGPAGP YAKESGIWAY YE

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.

Target Information

CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.