Thermo Fisher Scientific CHIA Polyclonal Antibody
인간 CHIA 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보존. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
- 카탈로그번호
- PA563681
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHIA. Recombinant protein control fragment (Product #RP-94208) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639766 |
Product Specific Information
Immunogen sequence:
DTGSNAYLNV DYVMNYWKDN GAPAEKLIVG FPTYGHNFIL SNPSNTGIGA PTSGAGPAGP YAKESGIWAY YE
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 85%
Target Information
CHIA degrades chitin and chitotriose and may participate in defense against nematodes and other pathogens.
There are three named isoforms produced by alternative splicing.
CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages.
It may act as a mediator of IL13-induced responses in Th2-dominated disorders such as asthma.
CHIA hydrolyzes N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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