Thermo Fisher Scientific NOLA3 Polyclonal Antibody
Thermo Fisher Scientific의 NOLA3 Polyclonal Antibody는 Human NOLA3 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot, IHC(P), ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 안정적인 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NOLA3. Recombinant protein control fragment (Product #RP-99053). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644737 |
Product Specific Information
Immunogen sequence:
PDDKYSRHRI TIKKRFKVLM TQQPRPVL
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and are classified into two families: C/D and H/ACA.
The H/ACA snoRNPs include the DKC1, NOLA1, and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted.
The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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