Thermo Fisher Scientific DDX3 Polyclonal Antibody
DDX3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Human, Mouse, Rat에서 반응합니다. Protein A로 정제된 고순도 항체로 안정적인 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human DDX3, amino acids 2–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the large DEAD-box protein family, defined by the conserved Asp-Glu-Ala-Asp (DEAD) motif, and exhibits ATP-dependent RNA helicase activity. It shows high RNA-independent ATPase activity and is stimulated by both RNA and DNA.
This protein functions in both nucleus and cytoplasm, contributing to transcriptional regulation, mRNP assembly, pre-mRNA splicing, mRNA export, translation, cellular signaling, and viral replication. Misregulation of this gene is linked to tumorigenesis. A paralog exists on the Y chromosome, and pseudogenes are found on chromosomes 4 and X. Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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