Thermo Fisher Scientific EPS8L1 Polyclonal Antibody
EPS8L1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 시료에 반응하며, 액상 형태로 제공. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 보장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPS8L1 (Accession Q8TE68), corresponding to amino acid residues Y416–L466 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850658 |
Product Specific Information
This antibody detects endogenous levels of total EPS8L1.
Target Information
Eps8L1 (EPS8-like 1), also known as DRC3 or EPS8R1, is a 723-amino-acid cytoplasmic protein belonging to the Eps8 (epidermal growth factor receptor pathway substrate 8) family. It is expressed in placental tissue and stimulates the guanine exchange activity of Sos1 (son of sevenless homolog 1), promoting the exchange of Ras-bound GDP for GTP.
Eps8L1 is associated with Actin and may play a role in membrane ruffling and remodeling of the Actin cytoskeleton. Through its ability to regulate protein activation and cytoskeleton dynamics, Eps8L1 participates in cell growth and differentiation. It contains one SH3 domain and is expressed as four isoforms due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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