Thermo Fisher Scientific CD1a (Mature Langerhans Cells Marker) Monoclonal Antibody (SPM120)
인체 CD1a 항원을 인식하는 SPM120 클론 단일클론 항체로, 성숙 랑게르한스 세포 마커로 사용됩니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용 가능하며, 단백질 A/G 정제, 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM120 |
| Immunogen | Human thymus cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD1a is a non-polymorphic MHC Class I-related cell surface glycoprotein expressed in association with beta-2 microglobulin. It is found on cortical thymocytes, Langerhans cells, interdigitating cells, and certain T-cell malignancies. CD1a mediates the presentation of lipid and glycolipid antigens to T cells. The human genome contains five CD1 family genes (CD1a, b, c, d, e) located on chromosome 1. CD1a localizes to the plasma membrane and early endocytic vesicles. Alternative splicing variants have been observed, though their biological significance remains uncertain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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