Thermo Fisher Scientific GeneBLAzer BDKRB1-NFAT-bla CHO-K1 Cells
Thermo Scientific™
GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells contain the human Bradykinin Receptor 1 (BDKBR1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.자세히 알아보기
GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells contain the human Bradykinin Receptor 1 (BDKBR1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells are functionally validated for Z` and EC50 concentrations of [Lys-des-Arg9]-Bradykinin. In addition, GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The Bradykinin-BDKRB1 receptor has been implicated in inflammation and pain. Preclinical evidence demonstrates that interruption of BDKRB1 receptor function causes analgesia under a variety of conditions and has been well established using selective antagonists and genetically modified mice.
For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
사양
등록 번호NM_000710
어세이 입력Cell-based beta lactamase reporter gene
셀 상태Dividing Cells
검출 방법Fluorescence
용도(애플리케이션)FRET
유전자 기호BDKRB1
개체군 상태Single Cell Clone Origin
제품라인GeneBLAzer™
수량2 x 106 Cells
리포터 유전자BLA (Beta-Lactamase)
타겟 입력BDKRB1
세포주CHO-K1
System TypeGeneBLAzer™
Druggable TargetGPCR
Unit SizeEach
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