Thermo Fisher Scientific Phospho-Histone H3 (Ser28) Recombinant Rabbit Monoclonal Antibody (HisH3S28-D6)
Recombinant rabbit monoclonal antibody targeting phospho-Histone H3 (Ser28). Suitable for WB and Flow Cytometry. Offers high specificity, lot-to-lot consistency, and animal origin-free formulation. For research use only.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HisH3S28-D6 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser28 of human phospho Histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745021 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it forms the nucleosome structure. Histones play key roles in transcription regulation, DNA repair, replication, and chromosomal stability. Post-translational modifications such as methylation, acetylation, and phosphorylation influence chromatin structure and transcription factor binding. The N-terminal tail of histone H3 can undergo multiple modifications affecting cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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