Thermo Fisher Scientific RAB29 Polyclonal Antibody
RAB29 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 사용 가능. Human, Mouse, Rat 반응성. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/glycerol buffer 보존.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB29 (Accession O14966), corresponding to amino acid residues N114–E164 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854388 |
Product Specific Information
Antibody detects endogenous levels of total RAB7L1.
Target Information
Rab GTPase acts as a key regulator in vesicle trafficking and is essential for maintaining the integrity of the endosome–trans-Golgi network structure.
Together with LRRK2, it participates in the retrograde trafficking pathway for recycling proteins such as mannose 6 phosphate receptor (M6PR) between lysosomes and the Golgi apparatus in a retromer-dependent manner.
It also regulates neuronal process morphology in the intact central nervous system (CNS) and may play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S. Typhi) epithelial cell infection.
{ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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