Thermo Fisher Scientific SAE1 Recombinant Rabbit Monoclonal Antibody (0L2N2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

0L2N2

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SAE1 (Q9UBE0). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SAE1,uniProtId:Q9UBE0-1,ncbiNodeId:9606,antigenRange:200-300,antigenLength:346,antigenImageFileName:MA5-42632_SAE1_Q9UBE0-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42632_SAE1_Q9UBE0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911773

Product Specific Information

Positive test controls include: 293T, MCF7, DU145, Mouse testis, Mouse thymus, Rat testis. The target is usually found in the following locations: Nucleus.

Immunogen sequence: DSSETTMVKK KVVFCPVKEA LEVDWSSEKA KAALKRTTSD YFLLQVLLKF RTDKGRDPSS DTYEEDSELL LQIRNDVLDS LGISPDLLPE DFVRYCFSEM A

Target Information

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2. form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.