Thermo Fisher Scientific Transferrin Receptor Monoclonal Antibody (7-1)
인간 Transferrin Receptor(CD71)을 인식하는 Mouse IgG2b 단일클론 항체. Western blot 및 ELISA에 사용 가능. Recombinant full-length human transferrin receptor를 면역원으로 제작. 2.3 mg/mL 농도, PBS buffer에 sodium azide 함유. 4°C 보관, 동결 금지.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7-1 |
| Immunogen | Recombinant, full length, human transferrin receptor protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.3 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_558274 |
Product Specific Information
MA1-20137 detects transferrin receptor in human samples.
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is recycled to the cell surface with a return to neutral pH and loss of affinity of apotransferrin for its receptor.
Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used to detect erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome, and HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA1-20137_Transferrin_Receptor_CD71_P02786-1_House_mouse.svg, MA1-20137_Transferrin_Receptor_CD71_P02786-1_House_mouse_PDP.jpeg)
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