Thermo Fisher Scientific KCNN3 (KCa2.3, SK3) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on sample size.
• The antibody is shipped as a lyophilized powder at room temperature and should be stored at -20°C upon arrival.
• Reconstituted solution can be stored at 4°C for up to 1 week.
• For long-term storage, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and influence neuronal firing patterns. Each AHP component is kinetically distinct and mediated by different calcium-activated potassium channels.
KCNN3, a member of the KCNN family, encodes a protein that contributes to the slow component of synaptic AHP and regulates neuronal excitability.
The encoded protein is an integral membrane protein forming a voltage-independent, calcium-activated channel with three other calmodulin-binding subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.