Thermo Fisher Scientific Phospho-RUNX1 (Ser276) Polyclonal Antibody
RUNX1 단백질의 Ser276 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot 및 면역세포염색에 적합. 인간, 마우스, 랫트 시료에 반응. 액상 형태로 제공되며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RUNX1 (Accession Q01196), corresponding to amino acid residues around phosphorylated Ser276. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816423 |
Product Specific Information
This antibody detects endogenous levels of RUNX1 / AML1 only when phosphorylated at Serine 276.
Target Information
RUNX1 belongs to the mammalian RUNX family of DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX1 is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac, and placenta. It is expressed in all tissues except brain and heart, with the highest levels in thymus, bone marrow, and peripheral blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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