Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI4G5), TrueMAB

Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI4G5), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CAMK2B (CaMKII beta) is a serine/threonine kinase involved in:

• Synaptic plasticity and vesicle mobilization
• Regulation of gene expression
• Long-term potentiation and neurotransmitter release in the CNS

There are four CaMKII isozymes (alpha, beta, gamma, delta), which may be co-expressed depending on tissue type.
CaMKII alpha is autophosphorylated on Thr286 upon Ca2+/CaM complex binding, a process known as Ca2+/CaM trapping, implicated in synaptic information encoding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.