Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI4G5), TrueMAB
CAMK2B 단백질을 인식하는 고특이성 단클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot 검증 완료, 1 mg/mL 농도의 동결건조 형태로 제공됩니다. 신경세포 내 시냅스 가소성 및 신호전달 연구에 적합합니다.
- 판매단위
- pk
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Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI4G5), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–385 of human CAMK2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CAMK2B (CaMKII beta) is a serine/threonine kinase involved in:
- Synaptic plasticity and vesicle mobilization
- Regulation of gene expression
- Long-term potentiation and neurotransmitter release in the CNS
There are four CaMKII isozymes (alpha, beta, gamma, delta), which may be co-expressed depending on tissue type.
CaMKII alpha is autophosphorylated on Thr286 upon Ca2+/CaM complex binding, a process known as Ca2+/CaM trapping, implicated in synaptic information encoding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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