Thermo Fisher Scientific SHP2 Polyclonal Antibody
SHP2 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal 항체. Western blot 및 IHC(paraffin) 실험에 적합. 고순도의 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적. 세포 신호 조절 연구 및 Noonan 증후군 관련 연구에 활용 가능.
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Thermo Fisher Scientific SHP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–6 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide YENVGLMQQQKSFR (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1960639 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX29214-PEP).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains, which act as phospho-tyrosine binding domains mediating substrate interaction. It is widely expressed in most tissues and plays a regulatory role in diverse cell signaling events such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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