Thermo Fisher Scientific DUSP22 Polyclonal Antibody
DUSP22 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 인간과 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 -20°C에서 안정합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human DUSP22 (aa 127–147, UniProt ID: Q9NRW4-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635335 |
Product Specific Information
This antibody detects endogenous levels of total DUSP22 (also known as JSP1) protein.
Target Information
Mitogen-activated protein (MAP) kinases are key components of cellular signaling pathways activated by various stimuli, mediating physiological and pathological cellular responses. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) family that selectively dephosphorylate phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by growth factors or cellular stress, serving as negative regulators of MAPK/ERK, SAPK/JNK, and p38 pathways. DUSP22 dephosphorylates ERK2 and JNK, and is most highly expressed in thymus, with detectable levels in monocytes and lymphocytes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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