Thermo Fisher Scientific APC2 Monoclonal Antibody (3A2G2)
Human APC2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합. Protein G로 정제된 액상 형태이며, 1 mg/mL 농도. 연구용으로 세포주기 관련 단백질 분석에 활용 가능.
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- MA531629
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Thermo Fisher Scientific APC2 Monoclonal Antibody (3A2G2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A2G2 |
| Immunogen | Purified recombinant fragment of human APC2 (AA: 2041–2181) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787253 |
Product Specific Information
MA5-31629 has been tested in indirect ELISA.
Target Information
APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins, ensuring that mitotic events occur in proper sequence.
APC2 contains cullin and RING finger domains important for regulating ubiquitination activity.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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