Thermo Fisher Scientific Pds5B Polyclonal Antibody
Rabbit polyclonal antibody targeting human Pds5B protein. Validated for WB, IHC, and IP applications. Provides high specificity for cohesin complex studies. Recommended storage at 4°C, for research use only.
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Thermo Fisher Scientific Pds5B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1400 and the C-terminus (residue 1447) of human Precocious Dissociation of Sisters-5B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
This gene encodes a protein that interacts with the conserved cohesin complex, which holds sister chromatids together and ensures accurate chromosome segregation during mitosis and meiosis. Pds5B acts as a negative regulator of cell proliferation and may function as a tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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