Thermo Fisher Scientific ALDH1A2 Polyclonal Antibody
Thermo Fisher Scientific의 ALDH1A2 Polyclonal Antibody는 Human, Mouse, Rat에서 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 비결합형 액상 항체로, retinoic acid 합성 관련 연구에 활용됩니다. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 2–245 of Human ALDH1A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547762 |
Product Specific Information
- Recommended positive controls: MCF-7, mouse testis, rat testis
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (81%), Japanese Medaka (81%), Xenopus laevis (88%), Dog (99%), Chicken (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein belongs to the aldehyde dehydrogenase family. The ALDH1A2 enzyme catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, a derivative of vitamin A, acts as a hormonal signaling molecule in both developing and adult tissues. Studies suggest that ALDH1A2 and CYP26A1 together regulate local embryonic retinoic acid levels, contributing to posterior organ development and preventing spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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