Thermo Fisher Scientific Phospho-INSR (Thr1160) Polyclonal Antibody
인간 INSR 단백질의 Thr1160 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 액상 형태, 0.25 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr1160 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen Affinity Chromatography |
| Storage Buffer | 10 mM HEPES, pH 7.5, with 100 µg/mL BSA, 50% glycerol, 0.15 M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2807481 |
Product Specific Information
Antigen affinity purified from pooled serum.
Target Information
INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes, and IGF-1R defects may also cause some forms of growth retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(PA5-95679_INSR_P06213-1_Rabbit.svg 및 PA5-95679_INSR_P06213-1_Rabbit_PDP.jpeg)
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