Thermo Fisher Scientific Phospho-Creatine Kinase MT (Tyr153) Polyclonal Antibody
Phospho-Creatine Kinase MT (Tyr153) 폴리클로날 항체로 마우스와 인간에 반응. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 미토콘드리아 크레아틴 키나아제 연구용으로 사용. 연구용 전용 제품으로 -20°C 보관.
- 카탈로그번호
- PA595676
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr153 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen Affinity Chromatography |
| Storage Buffer | 10mM HEPES, pH 7.5, with 100µg/mL BSA, 50% glycerol, 150mM NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| RRID | AB_2807478 |
Product Specific Information
Antigen Affinity Purified from Pooled Serum.
Target Information
Mitochondrial creatine (MtCK) kinase transfers high-energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes: sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes.
MtCK forms dimers and octamers, unlike cytosolic creatine kinase which forms only dimers. Overexpression of ubiquitous MtCK has been observed in malignant cancers with poor prognosis, possibly related to high energy turnover and reduced apoptosis.
Ubiquitous MtCK shares 80% homology with sarcomeric MtCK coding exons. Two genes located near each other on chromosome 15 encode identical mitochondrial creatine kinase proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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