
Thermo Fisher Scientific ACAT2 Monoclonal Antibody (OTI3E2), TrueMAB
ACAT2 단백질을 표적으로 하는 Mouse IgG2b 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, 안정적인 PBS/BSA/glycerol buffer 구성으로 연구용에 최적화되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E2 |
| Immunogen | Full length human recombinant protein of human ACAT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.
The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif.
This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis.
Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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