Thermo Fisher Scientific TAF4 Polyclonal Antibody
TAF4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ChIP assay에 적합합니다. 인간 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS(2% sucrose) 버퍼에 보관되며, -20°C에서 보존합니다.
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- pk
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Applications
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| ChIP assay (ChIP) | 0.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TAF4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2610532 |
Product Specific Information
Peptide sequence:
EQASDVRAQL KFFEQLDQIE KQRKDEQERE ILMRAAKSRS RQEDPEQLRL
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 78%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%
Target Information
TAF II p105 (also called TAF4B) is a cell-type specific transcriptional co-activator that is a component of the TFIID complex. It is expressed primarily in B cells and ovarian granulosa cells and interacts with OCBA/POU2AF1 to activate B cell-specific octamer-dependent transcription.
Additionally, TAF II p105 co-activates the transcription factor NFκB and is essential for activation of anti-apoptotic genes such as TNFAIP3.
TAF II p135 (also known as TAF4, TAF2C, TAF2C1, TAF4A, or TAFII130) is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and binds to proteins with glutamine-rich domains, such as the transcription factor CREB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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