Thermo Fisher Scientific PFKP Monoclonal Antibody (OTI5F7), TrueMAB
PFKP 단백질을 인식하는 마우스 모노클로날 항체로 Western Blot, IHC, Flow Cytometry에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol buffer에 보존됩니다. 연구용으로 세포 신호전달 및 대사 조절 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F7 |
| Immunogen | Full length human recombinant protein of human PFKP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including:
- Cyclic nucleotide-regulated protein kinase (PKA & PKG) family
- Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family
- Related to PKA and PKC (RAC/Akt) protein kinase family
- Kinases that phosphorylate G protein-coupled receptors family (ARK)
- Kinases that phosphorylate ribosomal protein S6 family (RSK)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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